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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
27.27
Human Site:
S434
Identified Species:
46.15
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
S434
R
S
R
E
L
E
I
S
V
Y
W
R
D
W
R
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
S434
R
S
R
E
L
E
I
S
V
Y
W
R
D
W
R
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
G484
R
A
R
E
L
E
I
G
V
H
W
R
D
W
R
Dog
Lupus familis
XP_547295
1021
115999
S471
R
S
R
E
L
E
I
S
V
Y
W
R
D
W
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
S433
R
S
R
E
L
E
I
S
V
Y
W
R
D
W
R
Rat
Rattus norvegicus
O08874
985
112050
S435
R
S
R
E
L
E
I
S
V
Y
W
R
D
W
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
G471
R
S
R
E
L
E
I
G
V
Q
S
K
X
X
X
Chicken
Gallus gallus
XP_422357
1013
114806
S460
R
S
R
E
L
E
I
S
V
Y
W
R
D
W
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
S429
R
S
R
E
L
E
I
S
V
Y
W
R
D
W
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
E133
D
E
Q
P
A
K
V
E
M
V
P
A
G
Q
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
V206
Y
Q
C
Q
I
C
T
V
V
V
H
K
R
C
H
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
L298
N
L
E
P
E
G
L
L
F
T
E
I
T
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
V559
Q
E
K
K
K
R
T
V
P
S
A
Q
L
G
S
Red Bread Mold
Neurospora crassa
P87253
1142
127954
C474
N
I
M
R
C
A
L
C
G
D
F
L
K
Y
S
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
80
100
N.A.
100
100
N.A.
53.3
100
N.A.
100
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
60
100
N.A.
100
N.A.
33.3
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
0
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
8
0
8
8
0
8
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
8
0
0
58
0
0
% D
% Glu:
0
15
8
65
8
65
0
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% F
% Gly:
0
0
0
0
0
8
0
15
8
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% H
% Ile:
0
8
0
0
8
0
65
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
8
8
8
0
0
0
0
0
15
8
0
0
% K
% Leu:
0
8
0
0
65
0
15
8
0
0
0
8
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
15
0
0
0
0
8
0
8
0
0
0
0
% P
% Gln:
8
8
8
8
0
0
0
0
0
8
0
8
0
8
0
% Q
% Arg:
65
0
65
8
0
8
0
0
0
0
0
58
8
0
65
% R
% Ser:
0
58
0
0
0
0
0
50
0
8
8
0
0
0
15
% S
% Thr:
0
0
0
0
0
0
15
0
0
8
0
0
8
0
8
% T
% Val:
0
0
0
0
0
0
8
15
72
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
58
0
0
58
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
50
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _